ADHD Medications - What Are the Side Effects?
Many people suffering from ADHD are prescribed medication for the condition. It can improve symptoms but it also can cause adverse effects. Talk to your doctor if you experience side effects.
The most frequently prescribed medication prescribed by healthcare providers for ADHD is stimulants. These medications increase the levels of brain chemicals referred to as neurotransmitters, which control attention and behavior.
Methylphenidate
Methylphenidate is a stimulant of first choice for treating ADHD in children and adults is the most commonly prescribed medication. It works by enhancing the activity in brain areas that control attention and behavior. Methylphenidate can also be used to treat other conditions such as narcolepsy. It can help patients with Narcolepsy to stay awake throughout the day and improve their ability to focus and pay attention.
This medication has a very high potential for abuse and is classified as a Schedule II drug in the US Drug Enforcement Agency. The medication is taken exactly as prescribed to lower the risk of abuse and the adverse negative effects. Methylphenidate may trigger psychotic symptoms in some people. It can also cause worse behavior and tics in some people with Tourette syndrome or bipolar disorder. People with these conditions should inform their doctor before starting this medication.
Consult your physician if there are any other health concerns or if you have an allergy to food or dyes. (For example tartrazine is a yellow dye that can be found in processed food items and some medications. If you're taking Adhansia XR). adhd and medication is known to interact with drugs, such as opioids, antidepressants and monamine oxide inhibitors. These include isocarboxazid, linezolid and methylene blue. rasagiline, Emsam, Zelapar, or the tranylcypromine.
Avoid drinking alcohol and other stimulant substances while taking methylphenidate. These drugs can affect your heart rate and blood pressure. The tablets with immediate release methylphenidate (Ritalin) and the chewable tablet with long-acting function and long-acting orally disintegrating capsule (Quillichew ER and Cotempla XR-ODT) contain phenylalanine. It can be risky if you have a genetic disorder known as Phenylketonuria (PKU).
Bupropion
Bupropion is an antidepressant medication that works within the brain to improve mood and decrease symptoms of ADHD. It is also used to treat depression and seasonal depression (SAD), which occurs in the winter months of fall and winter. It can also be used to help people stop smoking cigarettes by reducing cravings for nicotine and withdrawal symptoms.
Bupropion has been found to reduce ADHD symptoms in adults in a variety of studies. The fixed-effect RR pooled for improvement in week 6 (using an improvement that is clinically significant of 30 percent or more on the CGI scale) is 1.14 (95 percent 95% confidence interval 0.95 to 1.37) and overall response the proportion of improved subjects was 52 percent in the bupropion treatment group, compared to 37% in the placebo group.
Bupropion can cause serious and life-threatening interactions if taken in conjunction with other medications. These include antidepressants and sedatives along with blood pressure medications. It can also increase the risk of seizures in those who have seizures or high blood pressure. It is not recommended for certain medical conditions, and women who are pregnant or nursing are not advised to take it. Bupropion is available under the brand-name medication Wellbutrin SR, Wellbutrin XL, Zyban, Budeprion SR, Aplenzin, and Forfivo XL. It is also available in generic form.
Tricyclic antidepressants

Tricyclic antidepressants (abbreviated TCAs) are a group of medications that affect brain chemicals. They were among the first antidepressants developed. Although they are not utilized as a primary treatment for depression but they can be effective for some individuals. They work by preventing the reuptake of dopamine, serotonin, and noradrenaline, thereby increasing their presence in neurons. They can be used to treat a variety of other diseases, such as enuresis, pain syndromes such as fibromyalgia, as well as the phantom-limb syndrome.
TCAs can be prescribed as a single or together with stimulants and they can have a positive impact on the symptoms of ADHD. They can reduce the severity of ADHD symptoms and decrease anxiety, depression and impulsiveness. In addition, they may aid in managing tics, which are repetitive and uncontrollable sounds or movements, such as throat clearing or blinking.
TCAs can cause side effects such as dry mouth and sedation and can increase the risk of developing cardiovascular problems. These drugs may interact with other medications, such as anticholinergics, and should be avoided in pregnant women. These drugs are also known to cause teratogenic effects in animals and can cross the placenta. If you have any concerns discuss it with your doctor, as there are newer antidepressants that have a less harmful side-effect profile.
Selective serotonin Reuptake inhibition (SSRIs).
SSRIs are antidepressants that inhibit serotonin reuptake by neuronal cells and increase the amount of serotonin for signaling. They also reduce anxiety and the tendency to be impulsive. They are often used as adhd medications because they reduce symptoms in some people and can be helpful alongside other medication. SSRIs include fluoxetine, sertraline paroxetine and citalopram. They have linear pharmacokinetics and have a very low clearance from the human body. However, they are extensively processed by CYP450 enzymes within the liver. This results in variable blood levels.
These medications are also prescribed to treat various conditions, such as major depression disorder, bulimia nervosa, generalized anxiety disorder, panic disorder and posttraumatic stress disorder (PTSD). The SSRIs fluoxetine, escitalopram, and sertraline can help reduce PTSD fundamental symptoms. They aren't effective in treating other PTSD symptoms.
The SSRIs may cause a rare side effect of sexual dysfunction. If you're considering taking one of these medications, it is important to speak with your doctor. Many people have to try various types of ADHD medication before finding the one that suits them. Research and development of new medications is ongoing. It is important to inform all medications you are taking to your physician.
Selective norepinephrine Reuptake inhibitors (SNRIs).
When stimulant drugs don't work for adults suffering from ADHD Doctors often prescribe an antidepressant known as a selective norepinephrine reuptake inhibitor (SNRI). These medications increase the levels of two brain chemicals known as serotonin and norepinephrine. They also improve mood and reduce depression and anxiety.
The SNRIs are similar in their negative effects to TCAs but are safer. They are used to treat numerous ailments, including anxiety disorders as well as chronic pain, such as fibromyalgia and nerve pain. They can also be utilized as an additional treatment for depression. Examples of SNRIs are duloxetine (Cymbalta) and Venlafaxine (Effexor).
They work by preventing the reabsorption (reuptake) of norepinephrine, which is a natural reaction in the brain following neurotransmission. This causes a greater than normal release of norepinephrine in a phasic manner. The increased levels of norepinephrine help improve concentration and mood.
SNRIs aren't approved by the FDA for the treatment of ADHD however, certain doctors prescribe them as an alternative stimulant. They are typically taken orally as pills but they can also be used as patches or liquids. The FDA approved a oral SNRI known as viloxazine or Qelbree to treat ADHD among children and adolescents in April 2021. It does not have a potential for abuse and therefore is not classified as a controlled substance.
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
SNRIs are antidepressants that affect the levels of norepinephrine as well as serotonin in the brain. They are used to treat depression and anxiety disorders, but can aid in the treatment of symptoms of ADHD. A number of studies have proven that SNRI drugs, such as venlafaxine and duloxetine, can dramatically reduce the score of various ADHD tests. SNRIs may increase blood pressure or interact with other medications. Therefore, it is important to consult a physician before taking these drugs. Additionally, improperly discarded medications could cause harm to animals and people, so it is important to follow proper disposal instructions.
SSRIs and SNRIs are not approved by the FDA to treat ADHD, but doctors can prescribe them off-label. They are safe and effective, and have less negative effects than stimulants. Talk to your doctor about your child's health issues and discuss the pros and cons of these drugs.
SNRIs can raise the body's level of serotonin and norepinephrine, however, they are not appropriate for all. For example women who are pregnant or breastfeeding should not use SNRIs as they may be passed into breast milk. They should not be taken by those with high blood pressure, liver issues, or other cardiovascular conditions.
Selective dopamine Reuptake Inhibitors (DARPIs).
Many people with ADHD find medication helps them increase their concentration and focus. Some may also notice a decrease in their impulsive behavior. The medication is usually used with behavioral therapy and training to help people understand how to manage their symptoms. Finding the appropriate medication for each person requires time. During this process, doctors observe physical reactions to find the optimal balance of benefits and side effects.
Stimulant drugs, such as methylphenidate, increase the activity of specific brain chemicals that regulate memory and attention. While they are generally safe and effective for the majority of people, they can also cause serious side effects like diminished appetite and sleep problems. These effects usually disappear after several weeks as your body adjusts to the medication.
Adults and children alike can take non-stimulant medicines. They take longer to start working, but they do increase concentration and control of impulses. They include alpha-2-adrenergic antagonists (atomoxetine and viloxazine) and guanfacine.
Antidepressants can also be effective in treating ADHD. They can increase the neurotransmitter neopinephrine levels in the brain, and aid in depression and impulsive behavior. Bupropion, an antidepressant, has been used to treat ADHD. It was originally prescribed "off-label" for ADHD but the drug companies eventually came up with extended-release versions, and the FDA approved it as a treatment for this condition.